Introduction Infusion preparation in British PICUs uses the Rule of Six (ROS) which was developed for administration without infusion devices. This method is inaccurate.1 Regulators recommend standardised approaches to IV infusions to improve patient safety and quality of care.2 Administration set changes also have an association with resource use and central line infections. 3 We report the impact of fixed concentration infusions and reduced administration set changes on nursing time and infusion equipment cost.
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