Category: Infectious Diseases

OSH Manual of Childhood Infections: The Blue Book (4 ed.)

Posted onAuthorKieran Lamb

Author: Mike Sharland, Karina Butler, Andrew Cant, Ron Dagan, Graham Davies, Ronald de Groot, David Elliman, Susanna Esposito, Adam Finn, Manolis Galanakis, Carlo Giaquinto, Jim Gray, Paul Heath, Terho Heikkinen, Ulrich Heininger, Philipp Henneke, Irja Lutsar, Hermione Lyall, Federico Martinon Torres, Andrew Pollard, Mary Ramsay, Andrew Riordan, Fernanda Rodrigues, Emmanuel Roilides, Pablo Rojo, Delane Shingadia, Steve Tomlin, and Maria Tsolia
Format: Webpage Publisher: Oxford University Press
Published: 2016
Print ISBN-13: 9780198729228
DOI: 10.1093/med/9780198729228.001.0001

Antimicrobial agents either kill (bactericidal) or inhibit (bacteriostatic) the growth of a microorganism by targeting specific unique bacterial sites or metabolic pathways. Common antibiotic adverse effects and toxicities include allergic reactions, numerous possible toxicities, alteration of human flora, drug interactions, and promoting of antibiotic resistance. Presumptive and empirical therapy relies on the clinical syndrome and anatomical site of infection. Factors to consider when choosing empirical therapy include identification of the organism, the estimated benefit to the patient, the probable susceptibility of the isolated (or suspected) pathogen based on laboratory results or local epidemiological parameters, and pharmacokinetic/pharmacodynamic considerations. Host factors, including age, immune deficiency status, and other underlying conditions, should always be considered when choosing an antibiotic. There are few absolute indications for the prophylactic use of antimicrobials, and this is one area where misuse is common. The susceptibility of common pathogens is often predictable, allowing adequate empirical treatment. The main driver for the development of antibiotic resistance is the inappropriate use of antibiotics. Bacteria may be naturally resistant or may acquire resistance by means of DNA mutation or acquisition of resistance-conferring DNA from another source (e.g. plasmids). Mechanisms of antibiotic resistance include chemical modification of antibiotics, reduced uptake into cells, active efflux from cells, target site modification, overproduction of antibiotic target, and metabolic bypass of inhibited reaction. Control of resistance may be achieved through adherence to prescribing guidelines, restriction policies that reduce the use of certain antibiotics, and antimicrobial stewardship programmes

Oxford Textbook of Infectious Disease Control: A Geographical Analysis from Medieval Quarantine to Global Eradication

Posted onAuthorKieran Lamb

Author: Andrew Cliff and Matthew Smallman-Raynor
Format: Webpage Publisher: Oxford University Press
Published: 2013
Print ISBN-13: 9780199596614
DOI: 10.1093/med/9780199596614.001.0001

The Oxford Textbook of Infectious Disease Control discusses the issues of geographical spread of human communicable diseases. Split into six chapters it tackles surveillance, quarantine, vaccination, and forecasting for disease control. A wide selection of representative maps and diagrams are used to illustrate the ideas explored.

Oxford Handbook of General Practice (4 ed.)

Posted onAuthorKieran Lamb

Author: Chantal Simon, Hazel Everitt, Francoise van Dorp, and Matt Burkes
Format: Webpage Publisher: Oxford University Press
Published: 2014
Print ISBN-13: 9780199671038
DOI: 10.1093/med/9780199671038.001.0001

Fully revised to reflect the new changes to the GP contract and the GP curriculum, this fourth edition of the best-selling Oxford Handbook of General Practice is a practical guide to all aspects of general practice, including everything from vital clinical information to valuable practical guidance from experienced GPs. Comprehensively covering everything a doctor needs to work in, or manage a GP practice, this resource ensures readers are always up-to-date with the latest guidelines, the most recent protocols, and cutting-edge clinical information. It is fully illustrated, features many useful figures, diagrams, management boxes, and tables, and new full colour photographs have been added to the dermatology and ophthalmology chapters.

Oxford Handbook of Infectious Diseases and Microbiology (2 ed.)

Posted onAuthorKieran Lamb

Author: M. Estee Torok, Ed Moran, and Fiona Cooke
Format: Webpage Publisher: Oxford University Press
Published: 2016
Print ISBN-13: 9780199671328
DOI: 10.1093/med/9780199671328.001.0001

Reflecting the recent changes in postgraduate infection training, the Oxford Handbook of Infectious Diseases and Microbiology provides an integrated clincal infection overview. Practical and comprehensive, it builds on the first edition, covering the basics of antimicrobial therapy, bacteriology, virology, and parasitology, together with a detailed overview of clinical syndromes, diseases, and conditions. The authors are consultants in microbiology and infectious diseases in respected UK institutions and have worked together with trainees to produce a book that will be an essential companion for everyone caring for those with infection.

Oxford Handbook of Key Clinical Evidence (2 ed.)

Posted onAuthorKieran Lamb

Author: Kunal Kulkarni, James Harrison, Mohamed Baguneid, and Bernard Prendergast
Format: Webpage Publisher: Oxford University Press
Published: 2009
Print ISBN-13: 9780198729426
DOI: 10.1093/med/9780198729426.001.0001

Key trials have been selected for their relevance to clinical practice, allowing the reader to quickly access some of the most fundamental issues that influence their day-to-day activities. The Handbook covers all major medical and surgical specialties, with a new section on paediatrics added for the second edition. Introductory chapters have been included on the development of evidence-based medicine, giving uninitiated readers the tools required to critically analyse and understand medical studies. Complex trials have been distilled to key relevant facts, for quick reference and understanding. This is a comprehensive one-stop shop for medical students, trainees, and clinicians of all levels that presents key information for a selection of seminal evidence that has informed medical and surgical practice. Readers are introduced to the statistical methods and tools needed to critically analyse trial data, providing a key for the terms and statistical methods encountered in the book and within clinical research as a whole. Leading figures in the major specialties have selected and summarized some of the most important trials, while analysis of the key message and impact of the trial firmly places the evidence into a practical setting for the reader. Key study features and results are examined, while the difficulties or problems associated with the trials are outlined

Oxford Handbook of Expedition and Wilderness Medicine (2 ed.)

Posted onAuthorKieran Lamb

Author: Chris Johnson, Sarah R. Anderson, Jon Dallimore, Shane Winser, David Warrell, Chris Imray, and James Moore
Format: Webpage Publisher: Oxford University Press
Published: 2015
Print ISBN-13: 9780199688418
DOI: 10.1093/med/9780199688418.001.0001

Revised for its second edition to include the latest national and international guidelines, the Oxford Handbook of Expedition and Wilderness Medicine enables efficient preparation and planning before the journey, advises on camp logistics, risk management, and medical problems during the trip, as well as highlighting rare but important risks to those visiting remote areas. Focusing on preventative measures, it also contains chapters dealing with crisis management, emergency care, and evacuation from challenging environments. Now containing more guidance about the obligations of a clinician joining an expedition, and the ethical approach to such work, it also provides an increased emphasis on medicine in various extreme environments. With revised and additional illustrations, more colour plates, and an increased use of important algorithms, it has been updated with the support of the Royal Geographical Society, and incorporates the combined knowledge and experience of a team of experienced clinicians and expeditioners.

Oxford Handbook of Clinical and Laboratory Investigation (4 ed.)

Posted onAuthorKieran Lamb

Author: Drew Provan
Format: Webpage Publisher: Oxford University Press
Published: 2018
Print ISBN-13: 9780198766537

DOI: 10.1093/med/9780198766537.001.0001

nvestigation of patients with suspected disease has become highly complex, with an ever-expanding plethora of investigative techniques available to clinicians. This handbook details the techniques used in modern clinical medicine, across all the major specialties. Each chapter outlines the range of investigations available, along with preparation of the patient, complications, and interpretation of results. The handbook also includes a symptom-focused approach initially, which helps clinicians determine which system may be involved before, then reviews the specialty-specific sections of the book.

Emergencies in Clinical Medicine

Posted onAuthorKieran Lamb

Author: Piers Page and Greg Skinner
Format: Webpage Publisher: Oxford University Press
Published: 2010
Print ISBN-13: 9780199202522
DOI: 10.1093/med/9780199547197.001.0001

This reference aims to give the junior doctor the confidence to recognise these and manage emergencies. It is concise, didactic and an excellent complement to the Oxford Handbook of Clinical Medicine.

Medical Masterclass: infectious diseases and dermatology (module 5)

Posted onAuthorKieran Lamb

Pages: 335 Size: 11 MB Format: PDF Publisher: Royal College Of Physicians
Published: 01 January, 2010
eISBN-13: 9781860164378

Each module starts with case-studies that define the core content of a specialty by covering all of their most common clinical presentations; and then discusses the appropriate clinical approach, history taking, examination, differential diagnosis, investigations and management for each of them.

These case-studies are followed by a section for self-assessment and structured notes on specific diseases, treatments, investigations and practical procedures.

Davidson’s Essentials of Medicine

Posted onAuthorKieran Lamb

Author: Edited By J. Alastair Innes With A Contribution By Simon Maxwell.
Pages: 879 Size: 14.57 MB Format: PDF Publisher: Churchill Livingstone
Published: 17 March, 2015
eISBN-13: 9780702055959

For over half a century Davidson’s Principles and Practice of Medicine has informed and educated students, doctors and other health professionals all over the world, providing a comprehensive account of the practice of medicine. Davidson’s Essentials of Medicine provides the core content of the main textbook in a condensed format which will be invaluable whenever you are on the move – whether commuting, travelling between training sites, or on electives.