Medical Care for Adults with Down Syndrome.

Agency for Healthcare Research and Quality (AHRQ); 2026.

We selected randomized controlled trials and comparative nonrandomized studies that enrolled adult participants with Down syndrome to evaluate benefits and harms of screening, diagnostic, or treatment interventions. No studies addressing screening interventions were identified. We identified only a limited number of treatment interventions. Some improvements were observed for dementia, depression, sleep apnea, and mobility.

Freely available online

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Dementia Bulletin

from Mersey Care Evidence and Library Service

Credit to our coworkers over at Mersey Care

In this issue:

  • Dementia Caregivers’ Preferences for Involvement in Delirium Care During Hospitalization
  • Vocal Fold Atrophy in Patients With Alzheimer’s Disease and Related Dementias
  • How Does Receipt of Dementia Screening Impact Depressive Symptoms Among Patients and Their Family Members?
  • Cognitive Reablement Using Digital Voice Assistants for People Living With Dementia or Mild Cognitive Impairment: A Co‐Design Study
  • Plus much more

latest dementia bulletin

from Mersey Care Evidence and Library Service

In this issue:

  • Five benefits of getting a diagnosis for dementia – what are they?
  • Understanding diabetes and brain health
  • Can a Blood Test in Midlife Predict Your Alzheimer’s Risk?
  • New models of Down syndrome Alzheimer’s developed to improve understanding of condition
  • Plus much more

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Dementia Bulletin

Mersey Care Evidence and Library Service

In this issue:

  • Functional Implications of Marine Biosurfactants and Their Therapeutic Potential Against Alzheimer’s Disease
  • The proteomic and metabolomic signature of inherited chromosomally integrated HHV‐6 and its role in all‐cause dementia and mortality risk: The UK Biobank study
  • Age of Type 1 Diabetes Onset and Dementia Risk: A Swedish Nationwide, Register‐Based Cohort Study
  • Predictors of Alzheimer’s disease treatment optimism among a nationally representative sample of US older adults
  • Plus much more

dementia bulletin

from Mersey Care Evidence and Library Service

In this issue:

  • Dementia blood biomarkers in the context of post‐stroke cognitive outcomes: Systematic review and evidence synthesis
  • Income level and the risk of incident dementia among adults aged ≥50 with newly diagnosed type 2 diabetes: a population-based cohort study using the NHIS-Senior database in South Korea
  • Association between the use of anti-herpetic drugs and subsequent initiation of Alzheimer’s disease drug treatment: Dutch population-based inception cohort study
  • Development and temporal validation of a machine learning model to estimate total MoCA scores from telephone-based items in patients with mild cognitive impairment
  • Plus much more

Latest Dementia bulletin

Dear all,

The latest dementia bulletin from Mersey Care Evidence and Library Service has now been published at https://www.evidentlybetter.org/dementia/2026/04/28-april-2026/

In this issue:

  • Amyloid‐beta‐targeting monoclonal antibodies for people with mild cognitive impairment or mild dementia due to Alzheimer’s disease (Cochrane Review)
  • Social Health Experiences and Support Needs of People Living With Young-Onset Dementia: A Qualitative Study
  • Global burden of disease due to young-onset dementia and the forecast for 2050: update from global burden of disease study 2021
  • Low Vitamin D Levels Tied to Alzheimer’s Brain Changes
  • Plus much more

Please let us know if there are other people who you think might benefit from receiving this bulletin.

Dementia bulletin

Hi all,

The latest dementia bulletin from Mersey Care Evidence and Library Service has now been published at https://www.evidentlybetter.org/dementia/2026/03/30-march-2026/

In this issue:

  • Association of diabetes severity with cognitive function in US adults: a cross-sectional analysis of the AI-READI multicentre cohort
  • SAFER-Dem: generating co-designed adaptations to a discharge care planning bundle for people living with dementia
  • Nutritional status, Mediterranean diet adherence, and quality of life in older adults with dementia: A cross-sectional study
  • Plus much more

Please let us know if there are other people who you think might benefit from receiving this bulletin.

Dementia Bulletin

Hi all,

The latest dementia bulletin from Mersey Care Evidence and Library Service has now been published at https://www.evidentlybetter.org/dementia/2026/02/17-february-2026/

In this issue:

  • Development of a resource use measure to capture costs related to unpaid care for people living with non-memory led dementia: a modified Delphi study
  • Feasibility of the MAINTAIN intervention to support independence after a fall for people with dementia: a pilot cluster randomised controlled trial in participants’ own homes
  • Blood Sugar Spikes After Eating May Raise Alzheimer’s Risk
  • Reading and writing can lower dementia risk by almost 40%, study suggests
  • Plus much more

Please let me know if you think there are other colleagues who would benefit from receiving this bulletin and I will add them to the mailing list.

Virtual Reality and Dementia Care In England

Emerging Evidence and Future Directions

Sheppy B. British Journal of Healthcare Management 2025;31(10):1-4.
(Dementia represents one of the most significant public health challenges in England, affecting around 982000 individuals, with this figure predicted to reach 1.4 million by 2040 (Alzheimer’s Research UK, 2025). This article explores the emerging evidence base supporting virtual reality applications for people with dementia in England. It draws on research, theoretical models and policy developments, offering insights into how virtual reality could be integrated into dementia care pathways.)

Article link: Virtual reality and dementia care in England: emerging evidence and future directions | British Journal of Healthcare Management
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