Evidence updates

Recommendations for continued care and support of people who are clinically extremely vulnerable
Royal College of Physicians (RCP); 2020.
(Statement from the Royal College of Physicians, Royal College of Emergency Medicine, Royal College of General Practitioners, Royal College of Paediatrics and Child Health, National Voices and specialist societies highlighting the challenges faced by both doctors and patients in identifying and reducing the risks associated with COVID-19 for the most clinically vulnerable people.)

Expanding the primary care workforce in 2020/21 .
NHS England & NHS Improvement; 2020.
(Actions for CCGs, PCNs and STPs resulting from People Plan and Third phase of NHS response to covid-19.)

Reintroduction of NHS continuing healthcare.
Department of Health and Social Care (DHSC); 2020.
(Sets out how clinical commissioning groups (CCGs) will restart NHS continuing healthcare (CHC) assessment processes from 1 September 2020.Published 21 August 2020.)

Virtual training for midwives during a pandemic.
Abramson P. British Journal of Midwifery 2020;28(8):502–503.
(When a baby dies, it is a tragedy at any time but during the COVID-19 pandemic, bereaved families and the professionals supporting them have been faced with additional and often distressing challenges. Restrictions have made access to hospitals difficult for partners and other family members, while support services that would normally be provided for bereaved parents have been unavailable or severely limited.)

Ketamine as a mental health treatment: Are acute psychoactive effects associated with outcomes? A systematic review.
Grabski M. Behavioural Brain Research 2020;392:112629.
(The databases Medline, Embase and PsycInfo were searched. The studies reviewed displayed great variability in methodology and quality of reporting. The most commonly assessed effect was dissociation, measured by the CADSS. Our results suggest that the CADSS total is not consistently associated with antidepressant outcomes. Apart from this, the current literature is too limited to draw definite conclusions on an association between acute psychoactive effects and mental health outcomes.)


Coronavirus and the common cold

New research suggests that infection from a common cold could generate an immune response to COVID -19

The article focuses on one arm of the immune response – the B and T cells which produce antibodies. It shows that people keep T cells from the mild coronaviruses long enough to interact with a new challenge by SARS-CoV-2, meaning that those T cells might recognise SARS-CoV-2 and help to clear the infection. Could this possibly provide an answer as to why some people have less severe effects compared to others? Click here to read more.

To read the whole research, conducted by La Jolla Institute for Immunology click here.

Antibodies latching onto a coronavirus to neutralise it.
https://www.shutterstock.com/image-illustration/antibodies-attacking-sarscov2-virus-conceptual-3d-1700617951

BMJ Live

A free virtual conference

BMJ are hosting a live, virtual conference taking place between 15-17th October.

The event will feature a range of sessions covering clinical webinars, leadership skills, career progression, one-to-one careers advice and wellbeing. You can create your own online agenda so you can attend sessions the most relevant to your needs.

To book your place click here.

Evidence based summaries

Recent research and reports

Should antidepressants be used for major depressive disorder? Jakobsen JC. BMJ Evidence-Based Medicine 2020;25(4):130.
The benefits of antidepressants seem to be minimal and possibly without any importance to the average patient with major depressive disorder. Antidepressants should not be used for adults with major depressive disorder before valid evidence has shown that the potential beneficial effects outweigh the harmful effects.

Clinical pathways as a mobile device. Please log in via Athens to access the whole article. Barrett J. BMJ Evidence-Based Medicine 2020;25(4):131-137.
Overall, this project supports the development of a mobile application based on the design principles used in the clinical pathways. Providers did indeed use the clinical pathways. They found the pathways easy to use and helped provide evidence-based care in clinical practice. While the iPad was useful for some participants, a small sized tablet and phone would be preferred by others. Future work will be undertaken on mobile application development using multiple screen sizes.

Dementia prevention, intervention and care. The Lancet 2020;:doi.org/10.1016/S0140-6736(20)30367-6. Excessive alcohol consumption, traumatic brain injury, and air pollution have been added to the list of potentially modifiable risk factors for dementia. Together the 12 listed modifiable risk factors account for around 40% of worldwide dementia’s.

The Mental Elf

An online resource to keep up to date with mental health research and guidance

Mental heath experts summarise evidence based publications relevant to mental health practice.

They find key guidance, systematic reviews and high quality research and reports to help make your practice more evidence based.

You can also join evidence based journal clubs interactive webinars targeted at your field, or suggest a paper to be discussed.

Best of all, their work is free to read and access.

To access click this link.

Royal Marsden Manual

Update on accessing the resource

Further to our recent post about trouble accessing Royal Marsden Online, we can now confirm that this issue has been resolved. You can now access this resource by login in via their website here. Sorry for any inconveniences this has caused. If you have any further questions or queries about this resource, or any other electronic resources please contact the library services here.

Royal Marsden Access

Difficulties accessing the resource

We have been made aware that some members of the trust are having difficulty accessing Royal Marsden online. We are working towards getting this issue resolved and will inform you of updates when this issue has been rectified.

You can still access the latest materials, however you will need to login via Athens. Follow these simple steps:

  • Login to your Athens account here
  • Click on ‘My Resources’ (left hand side of the page)
  • Click on Wiley Royal Marsden Manual 10 (last on the list)
  • Search the content you were looking for